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for Piv- L Pro-
Fig. 8 (a) Final Rietveld refinement
g
-Abu-NHMe.
(b) Conformation of
Piv- L Pro-
-Abu-NHMe in the final refined crystal structure, showing the formation of an
intramolecular C-H O ΒΌ C hydrogen bond
g
been reported, continued progress in the development of methodology in this field
promises to pave the way for achieving this goal in the future.
6.2 Structure Determination of New Materials Produced
by Solid-State Grinding
In addition to the preparation of molecular cocrystals by conventional solution
phase crystallization, many materials (e.g. organic molecular cocrystals) can be
prepared only by grinding together two (or more) solid phases to generate a single
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