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Figure 2. Teleost phylogeny. Groups presenting a larval metamorphosis (
) and groups
presenting a secondary metamorphosis ( U ).
of TSH production at the time of amphibian metamorphosis (Denver
1999) (Fig. 3). As the thyrotropic axis is activated, a series of sequential
morphological transformations occur. An early change is the growth and
differential of the limbs, which in the absence of hormone, still form but
will not progress beyond the bud stage. The fi nal morphological change,
tail resorption, occurs when the level of TH is highest at the climax of
metamorphosis (for reviews: Kanamori and Brown, 1996; Tata, 2006).
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