Maxillofacial Bone Regeneration Using Tissue Engineering Concepts - Engineered Bone: Tissue Engineering Intelligence Unit - page 186

Figure 4. Experimental design of β -TCP and PRP for osteogenic capacity.
Figure 5. Histological findings of β -TCP and PRP.
than that of control sites at 2 and 4 weeks (Fig. 5). However, on the control sites, the bone
volume fraction was lower than that of β -TCP at 2 and 4 weeks.
These results suggest that the application of PRP causes a more rapid resorption of β -TCP
in a maxillary sinus. The change of morphology of the graft was observed in the early stage of
healing in both groups, indicating that the histologic differences were seen clearly especially in
the angiogenesis and absorption of β -TCP. And also PRP would have a potential to enhance
bone formation and improve the healing of the graft in a maxillary sinus. Taken together, the
present findings suggested that β -TCP loaded with PRP had excellent osteogenic characteris-
tics and supported its potential in tissue engineering to repair bone defects.