Barrier Maintenance in Neovessels - Mechanical and Chemical Signaling in Angiogenesis - page 220

28. Whitehead, K.J., Chan, A.C., Navankasattusas, S., Koh, W., London, N.R., Ling, J., Mayo, A.H.,
Drakos, S.G., Jones, C.A., Zhu, W., Marchuk, D.A., Davis, G.E., Li, D.Y.: The cerebral cavernous
malformation signaling pathway promotes vascular integrity via Rho GTPases. Nat. Med. 15(2),
177-184 (2009)
29. Schubert, W., Frank, P.G., Woodman, S.E., Hyogo, H., Cohen, D.E., Chow, C.W., Lisanti, M.P.:
Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific
nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1
null mice. J. Biol. Chem. 277(42), 40091-40098 (2002)
30. Siddiqui, M.R., Komarova, Y.A., Vogel, S.M., Gao, X., Bonini, M.G., Rajasingh, J., Zhao, Y.Y.,
Brovkovych, V., Malik, A.B.: Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration
and endothelial permeability. J. Cell Biol. 193(5), 841-850 (2011)
31. Thibeault, S., Rautureau, Y., Oubaha, M., Faubert, D., Wilkes, B.C., Delisle, C., Gratton, J.P.: S-
nitrosylation of beta-catenin by eNOS-derived NO promotes VEGF-induced endothelial cell
permeability. Mol. Cell 39(3), 468-476 (2010)
32. van Nieuw Amerongen, G.P., van Hinsbergh, V.W.: Targets for pharmacological intervention
of endothelial hyperpermeability and barrier function. Vascul. Pharmacol. 39(4-5), 257-272
(2002)
33. Augustin, H.G., Koh, G.Y., Thurston, G., Alitalo, K.: Control of vascular morphogenesis and
homeostasis through the angiopoietin-Tie system. Nat. Rev. Mol. Cell Biol. 10(3), 165-177
(2009)
34. van der Heijden, M., van Nieuw Amerongen, G.P., van Bezu, J., Paul, M.A., Groeneveld, A.B.,
van Hinsbergh, V.W.: Opposing effects of the angiopoietins on the thrombin-induced
permeability of human pulmonary microvascular endothelial cells. PLoS One 6(8), e23448
(2011)
35. van der Heijden, M., van Nieuw Amerongen, G.P., Chedamni, S., van Hinsbergh, V.,
Groeneveld, A.B.: The angiopoietin-Tie2 system as a therapeutic target in sepsis and acute
lung injury. Expert. Opin. Ther. Targets. 13(1), 39-53 (2009)
36. Komarova, Y., Malik, A.B.: FGF signaling preserves the integrity of endothelial adherens
junctions. Dev. Cell 15(3), 335-336 (2008)
37. Murakami, M., Nguyen, L.T., Zhuang, Z.W., Moodie, K.L., Carmeliet, P., Stan, R.V.,
Simons, M.: The FGF system has a key role in regulating vascular integrity. J. Clin. Invest.
118(10), 3355-3366 (2008)
38. Miyashita, Y., Ozawa, M.: Increased internalization of p120-uncoupled E-cadherin and a
requirement for a dileucine motif in the cytoplasmic domain for endocytosis of the protein.
J. Biol. Chem. 282(15), 11540-11548 (2007)
39. Wang, L., Dudek, S.M.: Regulation of vascular permeability by sphingosine 1-phosphate.
Microvasc. Res. 77(1), 39-45 (2009)
40. McVerry, B.J., Garcia, J.G.: Endothelial cell barrier regulation by sphingosine 1-phosphate.
J. Cell Biochem. 92(6), 1075-1085 (2004)
41. Lee, M.J., Thangada, S., Claffey, K.P., Ancellin, N., Liu, C.H., Kluk, M., Volpi, M., Sha'afi, R.I.,
Hla, T.: Vascular endothelial cell adherens junction assembly and morphogenesis induced by
sphingosine-1-phosphate. Cell 99(3), 301-312 (1999)
42. Sanchez, T., Estrada-Hernandez, T., Paik, J.H., Wu, M.T., Venkataraman, K., Brinkmann, V.,
Claffey, K., Hla, T.: Phosphorylation and action of the immunomodulator FTY720 inhibits
vascular endothelial cell growth factor-induced vascular permeability. J. Biol. Chem.

278(47), 47281-47290 (2003)
43. Hoffman, B.D., Grashoff, C., Schwartz, M.A.: Dynamic molecular processes mediate cellular
mechanotransduction. Nature 475(7356), 316-323 (2011)
44. Eyckmans, J., Boudou, T., Yu, X., Chen, C.S.: A Hitchhiker's guide to mechanobiology.
Dev. Cell 21(1), 35-47 (2011)
45. Adji, A., O'Rourke, M.F., Namasivayam, M.: Arterial stiffness, its assessment, prognostic
value, and implications for treatment. Am. J. Hypertens. 24(1), 5-17 (2011)
46. Sell, D.R., Monnier, V.M.: Molecular basis of arterial stiffening role of glycation.

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