CYANOBACTERIAL TOXINS - Cyanobacteria - page 499

Table 2: MC-variants due to change in positions of L-amino acids at Xaa(2) and Zaa(4) positions in the structure of
microcystins.

MC-Variant Xaa(2) Zaa(4) Organism Reference(s)

MC-LA Leucine Alanine M . aeruginosa

M. aeruginosa UTEX
B 2666
M . viridis

Botes et al . (1984);
Diehnelt et al . (2006);
Kaya and Watanabe (1990)

MC-Laba Leucine Aminoisobutyric acid M . aeruginosa

M. aeruginosa UTEX
B 2666

Gathercole and Thiel (1987);
Diehnelt et al . (2006)

MC-AR Alanine Arginine Microcystis spp.* Namikoshi et al .(1992a)

MC-YM Tyrosine Methionine M . aeruginosa Botes et al . (1984); Elleman et al . (1978)

MC-YA Tyrosine Alanine M . aeruginosa Botes et al . (1985)

MC-LR Leucine Arginine M . aeruginosa

Flos-aquae

Botes et al . (1985)
Krishnamurthy et al . (1989)
Rinehart et al . (1988);
Watanabe et al . (1988)
Sivonen et al . (1992a)

A. variabilis A.

M . viridis *

Anabaena strain
90; Anabaena spp.
Anabaena sp. strain
141; A . fl os-aquae
M . aeruginosa s train
B2666
M . aeruginosa
UTEX 2388
Antarctic*
cyanobacteria

Diehnelt et al . (2006)

Oh et al . (2000)

Jungblut et al . (2006)

MC-LY Leucine Tyrosine M . aeruginosa Stoner et al . (1989)

MC-FR Pheneylalanine Arginine Microcystis spp.* Namikoshi et al . (1992a)

MC-M(O)R Methionine

S-Oxide

Arginine Microcystis spp.* Namikoshi et al . (1992a)

MC-YM(O) Tyrosine Methionine S-Oxide M . aeruginosa Elleman et al . (1978);

Botes et al . (1985)

MC-RR Arginine Arginine M . aeruginosa

M . viridis *
Anabaena sp. strain 60
A . fl os-aquae
Anabaena sp strain 90;
sp. strain 141
Anabaena sp. strain 90;
sp. strain 202A1
M . aeruginosa UTEX
2388

Kusumi et al . (1987)
Painuly et al . (1988)
Watanabe et al . (1988)
Sivonen et al . (1992a)

Rapala et al . (1997)

Oh et al . (2000)

MC-YR Tyrosine Arginine M . aeruginosa

M . viridis *
M . aeruginosa UTEX
2388

Botes et al . (1985)
Watanabe et al . (1988)
Oh et al . (2000)

MC-HtyR Homotyrosine Arginine A . fl os - aquae Harada et al . (1991a)

MC-(H 4 ) YR 1,2,3,4,-

tetrahydrotyrosine

Arginine Microcystis spp. Harada et al . (1991a)

Table 2: contd....