Applications of FSI for Cardiovascular Haemodynamics - Computational Hemodynamics: Theory, Modelling and Applications - page 261

Fig. 8.28 Comparison of FSI and Rigid models for the image-based model ( a ) WSS distribution
at peak diastole ( t = 2�05 s ); ( b ) WSS variation over the last cardiac cycle at the bifurcation apex
point of view, which differs from angiography assessment conventionally used
by clinical study. The clinical study by Sun et al. (2011) reports that the mean di-
ameter of LCx in patients with a bifurcation angle θ > 80° was significantly larger
than that measured in patients with bifurcation angle θ < 80° due to the presence
of atherosclerotic plaques, and wider bifurcation angles are closely related to the
development of atherosclerosis, thus leading to coronary artery disease. Results
from this study are consistent with their reports as high tensile stress and low os-
cillatory wall shear stress simultaneously occur at the LCx side bifurcation shoul-
der in wider-angled models, high tendency of inducing atherosclerotic changes
are indicated.