Biology Reference
In-Depth Information
Table 22.
Molecular markers of germ cells of fi sh
Marker
Activity
Expression and function
Reference
vasa
DEAD box RNA helicase
PGC formation and
migration
Yoon et al. (1997),
Li et al. (2009)
ziwi
RNA-interacting proteins
Germ cell maintenance
Houwing et al.
(2007)
tudors
Tudor domain proteins
Germplasm component,
highly conserved across
phyla
Strasser et al. (2008)
bucky ball
Novel zebrafi sh gene
Balbiani's formation
Bontems et al.
(2009)
nanos1
RNA binding zinc fi nger
proteins
PGC migration, survival and
oocyte maturation
Koprunner et al.
(2001), Draper et
al. (2007) see also
Suzuki and Saga
(2008)
nanos2,3
RNA binding zinc fi nger
proteins
Germ cell marker
Aoki et al. (2008)
Fig. 33.
(A) Transverse section of medaka ovary consisting of (i) ovarian and (ii) stromal
compartments. Between these two compartments, note the presence of germinal epithelium
lined by the basement membrane. (B) A dorsal view of the ovarian cord in ovary of
sox9b-
EGFP transgenic medaka. 'Germinal cradles' (arrows) composed of germ cells and the
sox9b-
expressing cells are connected to each other by the cellular processes of
sox9b-
expressing cells
(arrow heads) to form the network, the 'ovarian cords' (from Nakamura et al., 2011. Ovarian
germline stem cells in the teleost fi sh, medaka (
Oryzias latipes
). Int J Biol Sci, 7: 403-409, with
permission of IJBS Publishing Team)
Color image of this figure appears in the color plate section at the end of the topic.
