Biomedical Engineering Reference
In-Depth Information
place for Wikipedia. With the recent shift in the life sciences to contribute data
to the public domain [96-98] (see Chapters 5 and 21), we are likely to see in the
very near future that they will provide additional precompetitive data [99] to
systems that can underpin the development of federated systems. These in turn
will allow pharmaceutical companies to link data across the abundance of life
science databases that are already and will increasingly become available. As
these data are made available to the community, we will see increasing usage
of such information-rich resources to be used for quantitative structure-activity
relationship (QSAR) modeling purposes, as has already been exemplifi ed pre-
viously by Ekins et al., who have used ChemSpider as a source of validated
chemical structures and matched against experimental properties [100-103]
In April 2010 ChemSpider was awarded a Best Practices Award by Bio-IT
for its community service [104] and in June 2010 was awarded an
I - Expo
innovation award [105]. The ChemSpider team remains focused on delivering
on the vision of developing a community portal for chemists to source data
and information. The collaboration of the community, data source providers,
and life science industry members in particular will be essential to ensuring
the ongoing expansion of the data and expansion of the reach of ChemSpider.
ChemSpider is likely to become one of the foundations of the Semantic Web
for chemistry and, with an ongoing focus for enabling collaboration and inte-
gration for life sciences, will be an essential resource for future generations.
ACKNOWLEDGMENTS
ChemSpider is the result of the aggregate work of many contributors. All core
ChemSpider development is performed by four developers: Valery Tkachenko (Chief
Technology Offi cer, RSC-ChemSpider, Lead Developer: ChemSpider), Alexey
Pshenichnov (Developer: ChemSpider), Jon Steele (Developer: ChemSpider), and
Sergey Shevelev (Lead Developer: ChemSpider SyntheticPages). ChemSpider is sup-
ported by a dedicated team of IT specialists. The author acknowledges the support of
the many data providers, curators, and users for their contributions to the development
of the data content in terms of breadth and quality.
REFERENCES
1. Williams AJ . ChemSpider and its expanding Web: Building a structure - centric
community for chemists.
Chem Int
2007 ; 30 ( 1 ): 30 .
2. Pence H , Williams AJ . ChemSpider: An online chemical information resource .
J Chem Educ
, Article ASAP. Available: http://dx.doi.org/10.1021/ed100697w .
3. PubChem . http://pubchem.ncbi.nlm.nih.gov .
4. The National Institutes of Health Roadmap Initiative . http://nihroadmap.nih.gov/ .
5. http://www.ncbi.nlm.nih.gov/pubmed .
6. How big is the challenge of curation and what is the structure of ginkgolide . http://
www.chemspider.com/blog/how - big - is - the - challenge - of - curation - and - what - is - the -
structure - of - ginkgolide - b.html .
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