Biomedical Engineering Reference
In-Depth Information
22.2.6.8 Patents
The linking of chemical records to patents offers scientists
direct access to information that may be of value to them in the scope of their
investigations of a chemical. As well as the ability to provide a direct link to
a patent via a URL, ChemSpider has been linked to the SureChem database
[17] using their public programming interface against the database. An
InChIKey [61] for the purpose of lookup retrieves a list of the fi rst three
associated patents and indicates the number of total records in their patent
database (covering U.S., European, Japanese, and World patents) that can be
accessed at their portal. The more indirect but nevertheless valuable approach
of searching the Google patent database using validated chemical identifi er
lookup has also been implemented. This approach presently only provides
access to U.S. based patents.
22.2.6.9 ChemSpider SyntheticPages
What ChemSpider is to the delivery
of information and data for chemical compounds, ChemSpider Synthetic
Pages (CS|SP) [25] intends to provide to chemists in regards to reaction syn-
theses. There is one caveat however—the community is fully responsible for
populating each record in the database as CS|SP is primarily a publishing
platform for chemists. While there are many commercial reaction databases
[85-87], there is no free database of synthetic routes that the community can
comment on, populate, and expand. CS|SP is a derivative work of the original
SyntheticPages project [88]. In a joint collaboration RSC-ChemSpider and the
SyntheticPages team have delivered a new architecture for the hosting of
synthesis procedures and enhanced the original data model such that the
platform can now host multimedia content and spectral data and allow seman-
tic markup and linking to the ChemSpider database and most importantly
enhanced capabilities for the deposition of synthesis procedures and data by
members of the community.
CS|SP is envisaged to be a manner by which chemists, and students specifi -
cally, can grow a professional online reputation for themselves as synthetic
chemists. Each SyntheticPage has a single author, the chemist who performed
the synthesis. The laboratory head or supervisor is credited via the association
of the synthesis with a particular research group. Following submission a
SyntheticPage proceeds through a review process by one or more members of
the editorial board made up of fi ve academic synthetic chemists [89]. Feedback
is provided to the author if necessary and edits can be made online. When the
SyntheticPage is published, the community can then provide direct feedback in
terms of additional questions, comments regarding their own experiences of
repeating the synthesis alternatives to the reported synthesis, and so on. In this
way this community research becomes an engaging dialog between synthetic
chemists as well as is representative of their skills and activities. Each
SyntheticPage receives a DOI [80] and makes a valuable addition to a resume.
As of August 2010 the database presently hosts almost 400 synthetic proce-
dures with new submissions being made on a regular basis. The intention is to
engage the community to participate in the further development of this rich
resource for chemistry. At present this database is an additional resource for
Search WWH ::
Custom Search