Biomedical Engineering Reference
In-Depth Information
Figure 21.1 Chembot and Chembot Bazaar prototypes would later evolve into the
Collaborative Drug Discovery (CDD) platform in 2007.
CDD Collaborate™ for private collaborations together with data in CDD
Public ™ .
21.3
CDD DATABASE TECHNICAL DETAILS
The development of the CDD database (Burlingame, CA) has been described
previously with applications for collaborative malaria research [19]. While the
following may be of lesser interest to general readers, it provides useful insight
into how the technology is implemented in comparison to alternative
approaches. The CDD database brings the power of cloud computing to drug
discovery, enabling collaborators to share research data securely within and
across organizations without the need to install and maintain complex soft-
ware. CDD runs on a fault-tolerant infrastructure providing redundant storage,
compute nodes, power, heating, ventilation, and air conditioning (HVAC), and
backbone connections. The infrastructure is also redundantly secure, protected
by multiple layers of host-based, network, and physical security measures.
CDD software runs on a MySQL database and was developed using the
Ruby and Java programming languages, leveraging particularly the power of
the Ruby on Rails Web application framework. Ruby on Rails is a modern
framework noted for enabling productive, “ quick and clean, ” well - factored
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