Biomedical Engineering Reference
In-Depth Information
example, both a microarray repository and a biospecimen repository need to
represent a source tissue, but since the two service specifi cations covered the
entirety of the systems (and hence would not be the same), there were not
appropriate incentives to standardize on the representation of a part of the
model.
To resolve this problem, the next generation of caBIG systems are being
designed to utilize services that are defi ned at a much different granularity to
improve reuse and promote working interoperability between systems. This is
accomplished by requiring that systems demonstrate compliance with specifi c
conformance statements that exist within the service specifi cation itself, rather
than simply demonstrating that the system provides an arbitrary semantically
defi ned service. The services themselves are defi ned through a formal enter-
prise architecture process based on the reference model for open distributed
processing (RM-ODP) and the specifi cations are defi ned by the NCI's enter-
prise conformance and compliance framework (ECCF). The ECCF is an
implementation of the HL7 services aware interoperability framework (SAIF)
and provides three levels of specifi cation: a conceptual model that describes
the function of the service and the types of data that it will utilize/provide, a
platform-independent model that includes the domain analysis model, and an
implementable platform-specifi c model that is defi ned for a particular technol-
ogy binding. By having three levels of specifi cation, it is possible for groups to
interact at different levels (using the same technology binding, domain model,
or conceptual model) with a clear understanding of the level of effort required
to enable those systems to interoperate.
Based on the requirements of the community, caBIG has devised an initial
catalog of needed services which will be implemented for use in the next
generation of systems. This “periodic table of services” is shown in Figure 17.3.
R t Oc o
EAeHxDxDsRa
Registration
Protocol
Study
Outcomes
Patient
Outcomes
Eligibility
Adverse
Event
Hx and
Physical
Discharge
Note
Decision
Support
Referral and
Authorization
Cr
S
Tp
I
L Rx
Sc
Scheduling
Credentialing
Specimen
Treatment
Plan
Image
Lab
Pharmacy
Qr
Mp
Ay
Sd
C
O
P
Pa
D
A
Data
Query
Protocol
Abstraction
Master
Problem List
SDTM
Correlation
Organization
Person
Disease
Agent
Allergy
Km Cm Ev Va Tx Au
Id
Tr Aa Py
Knowledge
Managemen
t
Contract
Management
Enterprise
Vocabulary
Validation
Translation
Audit
Id
Management
Trust
Managemen
t
Authorization
Authenticatio
n
Policy
Figure 17.3
Periodic table of services to support oncology research and care.
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