Biomedical Engineering Reference
In-Depth Information
EpsteineBarr Virus and Cytomegaloviruses
464
Mycotic Diseases
477
Viral Hepatitis Infections
464
Parasitic Diseases
477
Hepatitis A
465
Helminths
477
Hepatitis B
465
Acanthocephalans
477
Hepatitis C
465
Nematodes
478
Hepatitis D
466
Protozoa
479
Hepatitis E
466
Malaria
479
Callitrichid Hepatitis
466
Toxoplasmosis
479
Retroviral Diseases
467
Trypanosomiasis
479
Poxvirus Infections
468
Leishmaniasis
480
Other Viral Infections
469
Pneumocystis
480
Measles and Influenza
469
Amebiasis
480
Picornavirus Infections
470
Enteric Flagellate Infections
480
Arbovirus Infections
470
Cryptosporidiosis
480
Rubella
470
Lice and Mites
481
Rhabdovirus Infections
470
Model Occupational Health Program for Persons
Working with Nonhuman Primates
Adenovirus Infections
471
481
Papovavirus Infection
471
Introduction
481
Spongiform Encephalopathy Agents
471
Participants
481
Bacterial Diseases
472
Components
481
Systemic Infections
472
History and Physical Examinations
481
Tuberculosis
472
Serum Storage
481
Leprosy
473
Tuberculosis Screening
482
Salmonellosis
473
Immunizations
482
Tetanus
473
Tetanus Prophylaxis
482
Other Generalized Bacterial Infections
474
Rubeola (Measles) Prophylaxis
482
Gastrointestinal Bacterial Infections
474
Rabies Prophylaxis
482
Shigellosis
474
Hepatitis Prophylaxis
482
Campylobacteriosis
474
Other
482
Other Zoonotic Enteric Bacteria
475
Allergic Diseases
483
Respiratory Bacterial Infections
475
Physical Injury
483
Spirochetal Diseases
475
Records
483
Mycoplasmal Diseases
476
Health Services/Personnel
483
Rickettsial Diseases
476
Acknowledgments
483
Chlamydial Diseases
477
References
484
Many of the principles and basic approaches to safely
working with nonhuman primates and significant zoonotic
diseases are unchanged since the previous edition. There
have been many improvements in housing and safety
equipment, personal protective equipment, and techniques
for screening for potential zoonotic agents in a nonhuman
primates research colony, all of which reduce the hazards
and risks associated with this field of biomedical research.
Biosafety has always been an important aspect of working
with nonhuman primates in a laboratory setting. In recent
years the use of BSL-3 agents and Select Agents has
increased, and an even greater emphasis has been placed on
working safely with nonhuman primates in this type of
research setting. While much has been done to increase the
use of specific pathogen-free macaques in research, there
still remains a significant concern for working with these
species due to the potential exposure to B virus. This
chapter deals with the identification of hazards that may
pose a risk to workers and includes the naturally occurring
agents that have zoonotic potential as well as common
experimental agents that may be encountered. This edition
includes a number of experimental agents that were not
considered for use in nonhuman primate models but have
been added due to increased concern regarding possible
bioterrorist threats. Also, a number of agents that have not
been reported in many years, even in imported animals,
have been so noted in this edition in an effort to place the
proper emphasis on agents which are more likely to be
encountered. This does not mean that vigilant monitoring of
nonhuman primates for the presence of rare agents should
not be a part of the animal and human health surveillance
program. This chapter reviews real and potential hazards
related to working with nonhuman primates in a biomedical
setting and describes measures for keeping people safe from
naturally occurring and experimentally introduced patho-
genic organisms and from the animals themselves.
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