Biomedical Engineering Reference
In-Depth Information
Fig. 5.
Mean values of clustering variables,
k
=2
Fig. 6.
Mean values of clustering variables,
k
=3
Fig. 7.
Mean values of clustering variables,
k
=4
Multiway Cluster Comparisons.
Statistical significance of the observed differences
in the means among clusters was assessed by ANOVA and Kruskal-Wallis tests for mul-
tiway comparisons, and by
t
, and Wilcoxon rank sum tests for pairwise comparisons. A
nonparametric two-sample Kolmogorov-Smirnov test was also used to determine differ-
ences between pairs of clusters in the overall distributions of the bout duration quartile
variables. All
p
-values were corrected for multiple comparisons using the Benjamini-
Hochberg method on a per clustering basis, so that reported
p
-values are upper bounds
on the false discovery rate relative to all findings over the given family of
k
clusters.
Stage Bout Duration Quartile Means.
The results are as follows. For all clustering
families,
k
=2
,
3
,
4
, the mean values of the wake stage and stage NREM1 duration
quartile variables differ significantly among clusters in a multiway comparison using the
Kruskal-Wallis test (
p<
0
.
05
). ANOVA results are in agreement with Kruskal-Wallis,
with the exception that the inter-cluster difference in the quartile variable REM.Q1 is
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