Biomedical Engineering Reference
In-Depth Information
105
105
100
100
fitted curve
lower bound 95% CI
upper bound 95% CI
baseline trial1
baseline trial2
follow-up trial1
follow-up trial2
fitted curve
lower bound 95% CI
upper bound 95% CI
baseline trial1
baseline trial2
follow-up trial1
follow-up trial2
95
95
90
90
85
85
0
0.5
1
10
20
30
40
50
average speed (m/s) - reference data
normalized step length (% of hight)
Fig. 9. Normality compared to average speed.
Variables are well correlated, Spearman's rank
correlation coefficient r=-0.79, p < 0.0001.
The solid line indicates the linear model ap-
proximation a+bx, where a=95.5 with confi-
dence interval (CI) [94.9, 96.3]; and b=-2.6
with CI [-3.3, -1.9]. The dashed and dotted
lines indicate the 95% CI of predicted obser-
vations.
Fig. 10. Normality compared to average step
length. Variables are well correlated, Spear-
man's rank correlation coefficient r=-0.76,
p < 0.0001. The solid line indicates the lin-
ear model approximation a+bx, where a=95.5
with confidence interval (CI) [94.9, 96.3]; and
b=-2.5 with CI [-3.2, -1.8]. The dashed and
dotted lines indicate the 95% CI of predicted
observations.
A) EQ-5D mobility
B) EQ-5D pain/discomfort
100
100
95
95
90
90
85
85
ans 1
ans 2
ans 1
ans 2
Fig. 11. Normality compared to EQ-5D TM answers regarding (A) mobility and (B)
pain/discomfort. Mobility answers - ans 1: I have no problems in walking about; ans 2: I have
some problems in walking about. Pain/discomfort answers - ans 1: I have no pain or discomfort;
ans 2: I have moderate pain or discomfort.
tendency for better health to be accompanied by better normality index. This correla-
tion is particularly strong between normality and usual activities scores, Spearman's
r=0.75, p=0.0127. There was no correlation between the health scale in Part B of the
questionnaire and normality.
Improvement in normality was calculated as the difference between baseline and
follow-up values. Figure 13 shows how improvement in normality correlates with num-
ber of days spent at the ward after surgery. Although a Wilcoxon test indicated that
there was no statistically significant difference between groups, the Spearman's rank
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