Simulation of Prokaryotic Genome Evolution Subjected to Mutational Pressures Associated with DNA Replication - Biomedical Engineering Systems and Technologies - page 135

Fig. 6. The comparison of the average coding signal in simulations with selections run under
different mutational pressures. The change of the average coding signal was normalized by the
average coding signal at the start of the simulation.
Fig. 7. The accumulated numbers of genes from the leading and lagging strands damaged because
of the coding signal loss for different mutational scenarios
leading strand pressure is a direct pressure for the leading strand genes and reverse for
the lagging strand genes. Significantly less genes from the both DNA strands are elim-
inated when their sequences are under the changing pressure whereas the least genes
are damaged when they are under the influence of the lagging strand matrix. In the case