Simulation of Prokaryotic Genome Evolution Subjected to Mutational Pressures Associated with DNA Replication - Biomedical Engineering Systems and Technologies - page 134

Fig. 4. The average number of mutations accumulated in gene sequences during simulations with
three mutational pressures
Fig. 5. The comparison of the average coding signal in the simulation run with selection (dashed
line) and without selection (solid line). The change of the average coding signal was normalized
by the average coding signal at the start of the simulation.
we normalized the numbers of damaged genes accordingly. The number of genes elim-
inated because of their coding signal loss are the highest when genes are under the
mutational pressure typical of the leading strand (Fig. 7). It refers to the cases when the