Biomedical Engineering Reference
In-Depth Information
a
12
8
4
0
0
40
80
120
160
Sample Sequence No.
System Suitability Sample
CS and QC
Subjects 12&14
Subject 13
b
Disposable
Tips
Organic
Intermediate
Aqueous
CS/QC
Incurred Sample
Fig. 13
(
a
,
top
): Low internal standard responses were observed for incurred samples of some
subjects. (
b
,
bottom
): Due to variable thickness of intermediate layer between aqueous and organic
phases in liquid-liquid extraction, an inappropriately set aspirating height could result in partial
transfer of salt-containing intermediate layer, which caused ion suppression. Reproduced from ref.
[
36
] with permission from Elsevier
