Biomedical Engineering Reference
In-Depth Information
Fig. 10
Typical LC-MS/MS chromatograms of paclitaxel and docetaxel. Cell lysates were spiked
with paclitaxel to a final concentration equaling the LOQ (5 pg/mL) and with the I.S. docetaxel at a
final concentration of 300 pg/mL. Both SRM and HRSRM were evaluated. (
a
) SRM of docetaxel;
(
b
) HR-SRM of docetaxel; (
c
) SRM of paclitaxel; (
d
) HR-SRM of paclitaxel (Reproduced with
permission from Elsevier)