Biomedical Engineering Reference
In-Depth Information
where. p copy .is.the.operational.rate.of.the.copy-and-paste.operation,.and.the.fac-
tor.
1
L L − + . indicates. the. probability. of. selecting. a. particular. pair. of. c . and. k ..
The.occurrence.probability.of.case.A.is.given.as
1) 2
(
E t
A ( )
=
P
( , )
ξ
t P
( , ) .
ξ
t
(4.15)
.
Hence,.the.expected.destruction.of.ξ.in.this.case.is.calculated.as
P
( , )
ξ
t
=
PD E t
×
( )
A
A
A
.
(4.16)
L L
L L
g
g
p
L L
copy
=
[1
− ∆ ξ
( ,
V
;
ξ
,
G
)]
P
( , ) ( , )
ξ
t P
ξ
t
k
c k
,
2
(
+
1)
g
.
c
0
k
0
=
=
CaseB
ξ
n ..(A.transposon.is.copied.from.schema.ξ.and.pasted.onto.
another.schema. ξ n .where. ξ
= ξ
.and. ξ ∈
m
n .)
If. ′ξ = n .after.transposition,.schema.ξ.is.constructed..This.can.be.described.
by.the.regional.similarity.expressed.as
≠ ξ
∆ ξ
( ,
V
;
ξ
,
V
) ( ,
∆ ξ
V
;
ξ
,
V
′ ≠
) 0
⇒ ∆ ξ
( ,
V
;
ξ
,
G
) ( ,
∆ ξ
V
′ ξ
;
,
V
′ ≠
) 0.
.
k
n
k
k
n
k
k
c k
,
k
n
k
. (4.17)
The.constructive.rate. PC B .of.ξ.from. ξ n .is.then.obtained.by
L L
L L
g
g
p
L L
copy
PC
=
[
∆ ξ
( ,
V
;
ξ
,
G
) ( ,
∆ ξ
V
′ ξ
;
,
V
)]
.
(4.18)
B
k
c k
,
k
n
k
2
(
+
1)
g
.
c
=
0
k
=
0
while.the.selection.probability.of.a.particular.pair.of. ξ m .and. ξ n .is
E t
( )
=
P
( , ) (
ξ
t P
ξ
, ) .
t
(4.19)
.
B
n
Hence.the.expected.construction.of.ξ.in.this.case.is
P
( , )
ξ
t
=
PC
×
E t
( )
B
B
B
ξ ∈
S
n
ξ
p
L L
copy
.
(4.20)
=
2
(
+
1)
g
L L
L L
g
g
[
( ,
V
;
,
G
) ( ,
V
;
,
V P
)]
( , ) (
t P
, )
t
×
∆ ξ
ξ
∆ ξ
′ ξ
ξ
ξ
k
c k
,
k
n
k
n
ξ ∈
S
c
=
0
k
=
0
.
n
ξ
 
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