Tailor-Made and Biodegradable Vascular Scaffolds - Microsurgery: Advances, Simulations, and Applications - page 281

(i) Larger sieving range yielded MSPs with larger SD of diameter
while smaller sieving range yielded almost uniform size of
MSPs.

(ii) The diameter of all the MSPs were truly in the sieving range.

500

n=20

400

300

200

100

0

MSPs 1
150-500

MSPs 2

MSPs 3

Sieving range (Mm)

Figure 8.16 Relation between sieving range and diameter of MSPs. The
diameter of all the MSPs was truly in the sieving range.

8.7.2 Fabrication of Porous PLCL Sheet-Like Scaffolds by

Magnetic Sugar Leaching

Figure 8.17 shows the fabrication process of PLCL sheet-like
scaffolds. First, a specially coated silicon wafer was dried in a hot
oven (Fig. 8.17(a)). MSPs fabricated in the previous section were then
attracted to form an assembly by a neodymium magnet (magnetic
lux density: 0.122 T) located under the wafer (Fig. 8.17(b)). Then

polymer solution (PLCL 10 w% in chloroform) was dropped on
MSPs and vacuum was applied to ill the interspace between each
particle (Fig. 8.17(c)). After the complete evaporation of chloroform
and removal of the magnet, the composite with silicon wafer was
soaked in water to dissolve sugar. Finally, we obtained porous and
biodegradable scaffolds with well-connected pores (Fig. 8.17(d))
[42].