Patient-Specific Vascular Modeling - Microsurgery: Advances, Simulations, and Applications - page 111

drug (e.g., urokinase and t-PA) through the catheter might be well
reproduced. Meanwhile, it was conirmed that at least the following
differences were found between the experimental results obtained
with a solid vascular model and a membranous vascular model
respectively, which reproduced the same case:
1. State of blood streaming (especially, low in aneurysm)
2. Appropriate aneurismal embolism coil
This result shows that the vessel deformation during surgery
according to blood pulsation and catheter operation is too big
to be disregarded. Therefore, it was conirmed that the use of
membranous vascular model, which is able to reproduce the vascular
deformation, is appropriate in executing endovascular intervention
simulation. Moreover, although most of researchers have been
disregarding the existence of vessel deformation for hemodynamic
analysis, this result strongly suggests that such a precondition
would be improper. Thus, it was conirmed by this experiment that
the proposed vascular model is also valuable for the researcher of
science and engineering discipline besides the interventionalist and
other medical researchers. Meanwhile, although this chapter did not
mention, various medical equipment manufacturers (engaging in
catheter, medical tools, medicine, imaging system, etc.) pointed out
that the proposed vascular model is very useful for the performance
evaluation of medical equipment.
To evaluate the clinical utility of the vascular model proposed
in this research, ive different actual aneurismal models were
constructed from CT information. And, several clinical experiments
(blood low visualization, simulation of aneurismal embolization
and clipping, application to surgical planning and application to
medical imaging modalities) were executed, and the characteristic
and the utility of the vascular model were evaluated from different
viewpoint. Through these experiments, we conirmed that the
proposed vascular model is useful for simulating endovascular
intervention procedures, such as treatment for aneurysm and
thrombosis, and valuable for diagnosis and surgical planning for
individual patient. Especially, it was conirmed that the low state
and appropriate medical equipment become different according to
this vessel deformation.