Glutamate Carboxypeptidase II as a Therapeutic Target - Proteinases as Drug Targets - page 67

Table 3.2 Studies of GCPII localization in human tissues.

Study
citation 1 37 35 39 38 45 36 40 164 5 28 30 42 43 7 29 165

Utilized
antibody

7E11 7E11 7E11 7E11 7E11 J591,
J415,
J533,
E99

7E11 7E11 7E11 7E11, J591,
J415,
PEQ226.5,
PM2J004.5

7E11 7E11,
PEQ226.5

24.4E6,
7E11

Y-PSMA-1 GCP-04,
GCP-02

GCP-04 3/A12,

3/E7,
3/F11

Method of
detection

IHC IHC WB IHC IHC IHC IHC IHC IHC IHC IHC sandwich

immuno-
assay

IHC IHC WB, IHC WB, IHC IHC

Adrenal
gland

- - - - þ

Brain - - þ - - - þ þ þ þ

Breast - - - - þ þ þ - þ

Colon - - - þ - - þ þ - þ

Fallopian
tube

þ -

Gall
bladder

-

Heart - þ - þ -

Kidney þ þþ þ - þ - þ þ þ

Liver - - - - - - - þ þ

Lung - - - - - - - þ

Lymph
node

- - - - -

Ovary - - - - þ þ - þ

Pancreas - - - - þ -

Prostate þþþþþþ þþ þ þ þ þ þ

Salivary
gland

þ - þ

Skeletal
muscle

- þ - - - - -

Seminal
fluid

þ þ

Seminal
vesicles

- -