Biomedical Engineering Reference
In-Depth Information
Digestive and vascular system
GLP-1
(7-37),(7-36)
30, 31
His-Ala k Glu-Gly-Thr-Phe-
In vitro/in vivo
147-149,152
GIP
(1-42)
42
Tyr-Ala k Glu-Gly-Thr-Phe-
In vitro/in vivo
148,149
glucagon
(1-29),(3-29)
29, 27
His-Ser k Gln-Gly-Thr-Phe-
In vitro
153,154
PHM
(1-27)
27
His-Ala k Asp-Gly-Val-Phe-
In vitro
148
VIP
(1-28),(3-28)
28, 26
His-Serk Asp-Ala k Val-Phe-
In vitro
148,155
GLP-2
(1-33)
33
His-Ala k Glu-Gly-Ser-Phe-
In vitro/in vivo
152,156,157
GRP
27
Val-Pro k Leu-Pro-Ala
In vitro
158
PACAP
(1-27),(3-27),(1-38),(3-38)
27, 25, 38, 36
His-Ser k Asp-GlykIle-Phe-
In vitro
148,155
enterostatin
(1-5),(3-5)
5, 3
Val-Pro k Asp-Pro-Arg
In vitro
159
bradykinin
(2-9)
9
Pro-Pro k Gly-Phe-Ser-Pro
In vitro
160
BNP
(1-32)
32
Ser-Pro k Lys-Met-Val-Glu
In vitro/in vivo
161
GRF
(1-44/40/32/29)
44, 40, 32, 29
Tyr-Ala k Asp-Ala-Ile-Phe-
In vitro
148, 162-164
Nervous and endocrine system
vasostatin-1
(1-76)
76
Leu-Pro k Val-Asn-Ser-Pro
In vitro
165
substance P
(1-11),(3-11)
11, 9
Arg-Pro k Lys-Pro k Gln-Gln-
In vitro/in vivo
166-168
PYY
(1-36)
36
Tyr-Pro k
Ile-Lys-Pro-Glu-
In vitro/in vivo
169,170
NPY
(1-36)
36
Tyr-Pro k
Ser-Lys-Pro-Asp-
In vitro/in vivo
169,171
b-casomorphin
(1-7)
7
Tyr-Pro k
Phe-Val-Glu-Pro-
In vitro
172-176
endomorphin 2
(1-4)
4
Tyr-Pro k
Phe-Phe-NH
2
In vitro/in vivo
177,178
endomorphin-1
(1-4)
4
Tyr-Pro k
Trp-Phe-NH
2
In vitro
179,180
morphiceptin
(1-4)
4
Tyr-Pro k
Phe-Pro-NH
2
In vitro/in vivo
174
hemorphin-7
(2-9)
9
Tyr-Pro k
Tryp-Thre-Glut-Arg
In vitro
181
Immune system
RANTES (CCL5)
(1-68)
68
Ser-Pro
k
Tyr-Ser-Ser-Asp
In vitro
182-184
I-TAC (CXCL11)
(1-73)
73
Phe-Pro k
Met-Phe-Lys-Arg-
In vitro
184,185
eotaxin (CCL11)
(1-74)
74
Gly-Pro
k
Ala-Ser-Val-Pro-
In vitro
184,186
GCP-2 (CXCL6)
(1-77)
77
Gly-Pro
k
Val-Ser-Ala-Val
In vitro
183
SDF-1a/b (CXCL12)
(1-68/72)
68/72
Lys-Pro k Val-Ser-Leu-Ser-
In vitro
184,187-189
MDC (CCL22)
(1-69),(3-69)
69, 67
Gly-Pro k Tyr-Gly k Ala-Asn-
In vitro
184,190
IP-10 (CXCL10)
(1-77)
77
Val-Pro k Leu-Ser-Arg-Thr-
In vitro
182,184
LD78b (CCL3L1)
(1-70)
70
Ala-Pro k Leu-Ala-Ala-Asp-
In vitro
184,191
Grob (CXCL2)
(1-73)
73
Ala-Pro k Leu-Ala
In vitro
192
Mig (CXCL9)
(1-104)
104
Thr-Pro k Val-Val-Arg-Lys-
In vitro
184
Cleavage sites are indicated with an arrow, and DP4 cleaved dipeptides are indicated in bold.
BNP, B-type natriuretic peptide; GCP-2 (CXCL6), granulocyte chemotatic protein; GLP, glucagon like-peptide; GRF, growth-hormone-releasing factor; GRP,
gastrin-releasing peptide; IP-10 (CXCL10), interferon-g inducible protein; I-TAC (CXCL11), interferon inducible T cell a-chemoattractant; LD78b (CCL3L1)
human analog of MIP-1a; MCP-1/2/3 (CCL2/7/8), monocyte chemotactic protein-1/2/3; MDC (CCL22), macrophage-derived chemokine; NPY, neuropeptide Y;
PACAP, pituitary adenylate cyclase-activating peptide; PHM, peptide histidine methionine; PYY, peptide tyrosine tyrosine; RANTES (CCL5), regulated on
activation, normal T cell expressed and secreted; SDF-1a (CXCL12), stromal derived factor-1a; VIP, vasoactive intestinal peptide.
