Biomedical Engineering Reference
In-Depth Information
CHAPTER
8
Biochemical Reactions
and Enzyme Kinetics
John D. Enderle, PhD
OUTLINE
8.1 Chemical Reactions
448
8.5 Cellular Respiration: Glucose
Metabolism and the Creation
of ATP
8.2 Enzyme Kinetics
458
485
8.3 Additional Models Using
the Quasi-Steady-State
Approximation
8.6 Enzyme Inhibition, Allosteric
Modifiers, and Cooperative
Reactions
467
497
8.4 Diffusion, Biochemical Reactions,
and Enzyme Kinetics
8.7 Exercises
505
473
Suggested Readings
508
AT THE CONCLUSION OF THIS CHAPTER, STUDENTS WILL BE ABLE TO:
￿ Using the law of mass action, quantitatively
describe a chemical reaction using differential
equations.
￿ Using the law of mass action, quantitatively
describe enzyme kinetics using differential
equations.
￿ Describe and calculate the quasi-steady-state
approximation for chemical reactions.
￿ Simulate chemical reactions and enzyme
kinetics using SIMULINK.
￿ Use the quasi-steady-state approximation to
describe metabolism in a compartmental
model.
￿ Model biochemical reactions, enzyme kinetics,
diffusion, carrier-mediated transport and
active transport in a physiological system.
￿ Quantitatively describe the Na-K pump.
￿ Qunatitatively describe cellular respiration.
￿ Explain and model activators and inhibitors
in a chemical reaction.
 
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