Biomedical Engineering Reference
In-Depth Information
12. For a spherically focusing transducer with an aperture a
5 mm and a frequency of 5 MHz,
show which of the following combinations places the effective focal length for a target at a
depth of 40 mm.
(a) F
¼
¼
50 mm
(b) F
¼
40 mm
80 mm
13. For the Doppler detection of blood, a certain 2 MHz ultrasound system cannot sense signals
below a threshold of -35 dB. Assume a layer of muscle with negligible absorption loss above
a blood vessel where blood is flowing at a velocity of 1 m/s. Find the range of incident angles
(to the nearest degree) that will provide adequate signal strength and the corresponding
Doppler frequencies. Use Table 16.1 and note the Doppler angle
(c) F
¼
90 —incident angle.
14. For the arrangement of the whirling magnet in Figure 16.29, as d is increased, does the
intercepted voltage increase or decrease? What is a physical explanation for this effect?
(Note: Volt
¼
Weber/s.)
15. Determine the nuclear magnetic dipole moments, m z , for 1 H, 19 F, and 23 Na. Use Table 16.2.
16. Calculate the net magnetization moment M 0 for water at a temperature of T
¼
300 K and a
¼
10 19 protons/mm 3 . Use a form
magnetic field of B 0 ¼
0.5 T and a proton density of N
¼
6.7
X
M 0 ¼
^
of Eq. (16.54),
m n ¼ m n þ n
ð
Þ
and assume n þ ¼
N/2.
n
If B y ð t Þ¼ yB 1 sin o
, what will the field be in the rotated frame? After low-pass filtering to
eliminate 2o frequencies, what components are left?
ðÞ
17.
10 -5 T, what is
t p for 1 H? (b) Find the total flip time
18.
(a) For a flip angle of p
=
2 radians and B 1 ¼
2 angle followed by a p angle rotation.
19. Determine the relative decay for two individual rotations of p
for a p
=
=
2 and p in white matter and a
malignant tumor at the time
t ¼
250 ms. Which angle provides more contrast between the two
tissue types? Repeat at
t ¼
500 ms, and compare the contrast to the previous case.
20.
(a) Derive an expression for the spectrum of an F. I. D. pulse,
v
'(
t
)
¼ v
(
t
)H(
t
), where H(
t
)is
the step function, H(
t
)
¼
1 for
t >
0, and H(
t
)
¼
0 for
t <
0. Utilize the Fourier transform pair,
¼
1
i
2p f = a
` e a j t j H ð t Þ
h
i
. (b) What is the complex ratio of the F.I.D. spectrum to that of
2
j a j
1
þð
2p
f = a Þ
the spin echo? (c) Find the value of this ratio at the Larmor frequency. (d) Can you find an
explanation for this ratio based on the time waveforms involved?
2
21.
(a) If
5 ms for the F. I. D. pulse of problem 20, find the spectral component at
the Larmor frequency of 5 MHz for the conditions
T 2 ¼ T
¼
1cm 3 , and
B 1 ¼
20 m T
,I
¼
1A,V oxel ¼
10 12 J/(T-mm 3 ). (b) How does this value compare for a similar spectral magnitude
of a spin echo with T 2 for fat at the same Larmor frequency?
22. Find the -6 dB width of the envelope of a time pulse and the two end frequencies needed
to scan a 1-mm-thick slice from -15 cm to
0
xy ¼
M
5
þ
15 cm around an isocenter on the
-axis. Assume
z
G z ¼
0.5
/
.
T
m
23.
(a) In order to cover a range of
10 cm about an isocenter along the
y
-axis, phase encoding is
for 1 H and an overall phase shift of p
applied with a pulse length
t p ¼
10 m
s
=
2. Find the
slopes, G ym , at the end points and the slope resolution for 256 steps.
Continued
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