Biomedical Engineering Reference
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Layer 1
Layer 2
Layer 3
Layer 4
Layer 5
μ A1 ( x )
A 1
w 1
ŵ 1
N
Π
x
ŵ 1 f 1
μ A2 ( x )
A 2
x y
f
Σ
B 1
μ
B1 ( y )
ŵ 2 f 2
y
Π
N
B 2
w 2
ŵ 2
μ
B2 ( y )
Fig. 2.13 Adaptive neuro fuzzy inference system with the total five layers. Based on the
incoming elements (x and y), this system is composed with two layers of adaptive nodes (layers 1
and 4) and three layers of fixed nodes (layers 2, 3, and 5). The layer 1 is characterized by a
membership function l( ) that assigns each incoming element to a value between 0 and 1. Layer 4
is trained by a least squares method
We summarized the prediction accuracy and a representative feature for each
method of the model-free approach, as shown in Table 2.3 .
2.3.3 Hybrid Prediction Algorithms
Hybrid prediction algorithms used united methods to combine more than two
methods or approaches to obtain outstanding results, compared to a previous
solitary method. This method includes (1) adaptive neuro-fuzzy interference sys-
tem (ANFIS) [ 80 , 97 ], (2) hybrid model with adaptive filter and nonlinear model
(Adaptive Tumor Tracking System) [ 68 , 98 ], and (3) interacting multiple model
(IMM) filter [ 72 , 81 , 83 ].
2.3.3.1 Adaptive Neuro-Fuzzy Inference System
A adaptive neuro-fuzzy inference system (ANFIS) is a hybrid intelligent system
with combining both learning capabilities of a neural network and fuzzy logic
reasoning, to find a specific model in association with input breathing motion and
target prediction. The proposed neuro-fuzzy model ANFIS in [ 80 ] is a multilayer
neural network-based fuzzy system in combination with two layers of adaptive
nodes (layer 1 and 4) and three layers of fixed nodes (layer 2, 3, and 5), as shown in
Fig. 2.13 [ 80 ].
The first layer is distinguished by a fuzzy set (A 1 ,A 2 ,B 1 ,B 2 ) that is expressed
by a membership function to assign each incoming element to a membership value
between 0 and 1, as the following equation:
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