Microelectrodes for in-vivo determination of pH - Electrochemical Sensors, Biosensors and Their Biomedical Applications - page 257

CHAPTER 10
Microelectrodes for in-vivo determination
of pH
David Daomin Zhou
10.1 Introduction
10.1.1 Signifi cance of pH measurement in vivo
10.1.2 Techniques of measurement of pH in vivo
10.1.3 Advantages of microelectrodes for the determination of pH
10.2 Characterization of pH microelectrodes
10.2.1 pH and pH measurements
10.2.2 Calibration curve and linear response slope of pH microelectrodes
10.2.3 Sensitivity
10.2.4 Response time
10.2.5 Reproducibility/accuracy
10.2.6 Selectivity
10.2.7 Stability and reliability
10.2.8 Biocompatibility
10.3 Fabrication of microelectrodes for pH determination
10.3.1 Glass-based pH microelectrodes
10.3.2 Polymer membrane-based pH microelectrodes
10.3.3 Silicon-based pH microelectrodes
10.3.4 Metal/metal oxide-based pH microelectrodes
10.3.5 Ag/AgCl reference microelectrodes
10.4 Advanced microelectrode systems for pH determination
10.4.1 All-solid-state pH microelectrodes
10.4.2 pH microelectrode for a lab-on-a-chip
10.4.3 Microelectrode arrays for pH mapping
10.4.4 Microelectrodes for continuous recording of pH in vivo
10.4.5 Implantable pH microelectrodes
10.4.6 Wireless pH measurement systems
10.5 In-vivo applications of pH microelectrodes
10.5.1 pH in the body
10.5.2 Measurement of pH in blood
10.5.3 Measurement of pH in the brain