Biomedical Engineering Reference
In-Depth Information
A
10
8
10
7
10
6
10
5
10
4
10
-3
10
-1
10
1
10
3
10
5
f
/ Hz
B
10
6
10
5
10
4
10
3
100
200
300
t
/ h
Figure 4. A) Absolute value of the impedance |
Z
|(
f
) of a
functionalized porous alumina substrate prior the addi-
tion of the vesicle suspension (Ŷ). (Ƒ) depicts the imped-
ance data obtained 30 hours after vesicle addition. The
solid line is the result of a fitting routine using the equiv-
R
m
= 82 Mȍ. B) Change in membrane resistance
R
m
as a
function of time as a measure of long-term stability of a
pore-suspending bilayer preparation. After the pore-
suspending membrane had been established, impedance
spectra were taken every hour and the membrane re-
sistance was extracted from the impedance data. Around
50 hours after vesicle addition, rupturing of the mem-
branes becomes discernable as a decrease in membrane
resistance. Electrolyte: 0.1 M NaCl.
35
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