Biomedical Engineering Reference
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A
10 9
R el
10 7
R m
C m
10 5
10 3
B
-90
-60
-30
0
10 -2
10 -1
10 0
10 1
10 2
10 3
10 4
10 5
10 6
f
/ Hz
C
0
-20
-40
-60
-80
0
50
100
150
200
250
t
/ s
Figure 2. Bode representations of the impedance
data [A) Magnitude of the impedance, B) phase
angle between current and voltage] of gold-
covered porous alumina membranes functional-
ized with a DPPTE-monolayer before (Ŷ) and one
day after (Ƒ) the application of DPhPC dissolved
in n -decane on the porous alumina substrate to
form a nano-BLM. The solid lines are the results
of the fitting procedure to (Ƒ) using the equivalent
circuit shown in the inset: C m = 11.7 nF, R m = 4.7
Gȍ. Inset: Equivalent circuit composed of a paral-
lel RC -element ( R m and C m ) representing the elec-
trical behaviour of a lipid bilayer in series to an
Ohmic resistance R el that represents the electrolyte
solution and the wire connections. 24 C) Time-
resolved increase in I(10 6 Hz) during the mem-
brane formation process, allowing to follow the
kinetics and success of the thinning process. Elec-
trolyte: 1 M KCl, 1 mM CaCl 2 , pH 6.0. 26
 
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