Biomedical Engineering Reference
In-Depth Information
5 μm
2 μm
Figure 26.6
Experimental. results. of. images. with. Fe. beads. with. diameters. of. 1.μm,. imaged. through. an. agar. solu-
tion.. (Reproduced. by. permission. from. Springer. Science+Business. Media:. BioNanoSci., . Biomedical. super.
resolved.imaging.using.special.micro-probe,.1(3),.2011,.103-109,.Shahmoon,.A.,.Slovin,.H.,.and.Zalevsky,.Z..
Copyright.2011.)
and.rectangles.appearing.in.the.left.side.of.the.backward.transmitted.image..Figure.26.5b.
shows.a.square-like.shaped.resolution.target.at.different.locations..This.igure.demonstrates.
that.although.the.micro.probe.is.very.thin.in.its.diameter,.a.large.ield.of.view.is.obtained.by.
proper.cascading.of.the.collected.images.
In.order.to.further.demonstrate.the.high.spatial.discrimination,.we.repeated.the.experi-
ment. depicted. in. Figure. 26.6.. There. we. performed. imaging. of. Fe. micro. beads. through.
agar.solution..The.purpose.of.this.experiment.is.to.show.that.imaging.through.biological.
medium.is.possible.and.also.to.demonstrate.the.high.spatial.resolution.of.the.fabricated.
prototype.that.allows.spatial.separation.between.sub-micron.features.
Figure.26.7.presents.imaging.of.rat.heart.muscle.growth.on.a.slide..Figure.26.7a.shows.
a.top.view.microscope.image.of.the.rat.heart.muscle,.while.Figure.26.7b.shows.these.cells.
(shown.in.the.inset.image.of.Figure.26.7a).imaged.with.the.special.micro.probe..Cell.cul-
ture.and.sample.preparation.for.measurements.was.as.follows:.Rat.cardiac.myocytes.were.
(a)
(b)
Figure 26.7
(See companion CD for color igure.) .Imaging.of.rat.heart.muscle..(a).Top.view.microscope.image..(b).Image.of.
the.rat.heart.muscle.shown.in.the.inset.of.the.left.image.by.the.micro.probe.
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