Biomedical Engineering Reference
In-Depth Information
with.the.same.probe..In.the.experimental.results.obtained.with.one.of.our.prototypes.we.
were.able.to.obtain.biomedical.images.with.resolutions.of.about.5000.pixels.(10,000.pixels.
is.typical.high.resolution.endoscope),.while.the.used.probe.had.external.diameter.of.less.
than. 200.μm.. In. our. experiments. the. captured. high. resolution. images. were. transmitted.
backward.through.the.proposed.probe.to.a.camera.positioned.at.its.other.end.
26.2 Experimental Results
In.Figure.26.1.we.schematically.describe.the.operation.principle.related.to.imaging.capa-
bility.of.the.proposed.multifunctional.multi-core.probe.
In.respect.to.its.imaging.related.property,.the.probe.is.actually.a.transmission.medium.
that.transfers.the.optical.wave.front.arriving.from.the.object.at.its.input.edge.to.its.output.
edge,.from.which.it.continues.to.propagate.toward.the.resulted.image.plane..In.a.sense,.the.
input.and.output.edges.of.the.probe.act.similarly.to.principle.planes.of.an.imaging.lens.
The. optical. cores. of. the. proposed. probe. act. to. transmit. backward. the. wave. front. and.
to.generate.the.image;.however,.one.of.the.cores.can.also.be.used.to.illuminate.the.object.
itself. or. even. to. heat. it. if. illuminated. with. high. photonic. power. density.. The. obtained.
imaging.relation.is
1
1
1
+
=
.
(26.1)
U U
+
V F
.
1
2
while. the. input. and. output. planes. of. the. multi-core. probe. act. as. principle. planes. of. an.
imaging. lens. in. the. sense. that. they. transmit. the. wave. front. distribution. from. the. input.
to.the.output.plane..
U
1
,.
U
2
,.and.
V
.are.the.distances.between.the.object.and.the.end.of.the.
probe,. the. end. of. the. probe. and. the. imaging. lens,. and. the. imaging. lens. and. the. image.
detection.array,.respectively..
F
.is.the.focal.length.of.the.imaging.lens.
As.previously.mentioned,.the.micro.probe.is.not.only.thin.but.also.multifunctional..The.
multifunctionality. is. obtained. by. fabricating. a. multi-core. iber. with. metallic. nanowires.
interlaced. between. its. optical. cores. or. by. sputtering. metallic. materials. on. the. two. faces.
of.the.rectangular.shape.of.the.micro.probe..Those.wires.can.be.used.to.realize.thermo-
electric. cooling. (for. heating. and. cooling. related. medical. treatments). if. the. wires. are.
Input plane
Output plane
F
Multi-core probe
Image
Object
U
1
U
2
V
Figure 26.1
Schematic.description.of.the.imaging.operation.principle.of.the.probe..(Reproduced.by.permission.from.Springer.
Science+Business.Media:.
BioNanoSci.,
.Biomedical.super.resolved.imaging.using.special.micro.probe,.1(3),.2011,.
103-109,.Shahmoon,.A.,.Slovin,.H.,.and.Zalevsky,.Z..Copyright.2011.)
