Biomedical Engineering Reference
In-Depth Information
their.roles.and.functions.in.vitro.and.in.vivo.is.critical.before.fully.realizing.the.biomedical.
potential.of.NDs..Further.considerable.problems.include.immunogenicity,.diffusivity,.and.
metabolism.of.NDs.such.as.the.non-speciic.accumulation.of.the.nanoparticles.in.reticu-
loendothelial.systems..Another.important.issue.is.the.development.of.multimodal.imag-
ing.methods.to.allow.facile.detection.and.monitoring.of.the.particles.in.vivo..Developing.
simpler. and. safer. technologies. to. meet. the. demands. of. regulatory. concern. will. greatly.
help.in.future.diagnosis.and.disease.treatments..Successfully.addressing.the.aforestated.
challenges.will.accelerate.further.development.of.this.novel.nanomaterial.for.numerous.
other.exciting.and.beneicial.applications.
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