Biomedical Engineering Reference
In-Depth Information
+
N
O
3
O
9
S
+
O
Au
S
O
N
9
3
S
O
O
9
+
N
β-Galactosidase
(pl = 5.3, 465 kDa)
Cationic Au nanoparticle
(diameter: ca. 7 nm)
3
(a)
(b)
+
Water
Water
Water
Hybrid enzyme-nanoparticle
conjugate formation
1.
Addition of oil
Au nanoparticles enzymes
2.
Emulsification
Substrate
Enzymatic reaction
Oil
Water
Product
(c)
Figure 15.5
(a).Structure.of.β-gal..(b).Chemical.structure.of.cationic.gold.nanoparticles..(c).Formation.of.enzymatic.micro-
capsules. through. electrostatic. assembly. of. enzymes. and. nanoparticles. in. water. followed. by. assembly. of. the.
resulting.enzyme-nanoparticle.conjugates.at.oil-water.interfaces..A.cross-sectional.view.of.an.enzymatic.micro-
capsule.is.shown.in.the.bottom.left-hand.corner..(Samanta,.B.,.Yang,.X.C.,.Oir,.Y..et.al.:.Catalytic.microcapsules.
assembled.from.enzyme-nanoparticle.conjugates.at.oil-water.interfaces..
Angew. Chem. Int. Ed
..2009..48..5341-5344..
Copyright.Wiley-VCH.Verlag.GmbH.&.Co..KGaA..Reproduced.with.permission.)
