Bioresponsive Nanoparticles for the Intracellular Delivery of RNAi Therapeutics - Nanotechnology for the Delivery of Therapeutic Nucleic Acids - page 141

Figure 6.3 rHB sizes and reducibility. Atomic force microscopy images of

polyplexes without (A) or with (B) incubation for 30 min in
25 mM dithiothreitol (DTT) at 37°C. (C) Particle size distribu-
tion with a best-fit curve superimposed for rHBs without DTT
(top panels) and with DTT (lower panels). From J Drug Target ,

2010; 18(10): 812-820.