Biomedical Engineering Reference
In-Depth Information
Chapter 12
Osteoblast Behavior on Nanostructured
Implant Materials
Karolina Jurczyk a, * and Mieczyslawa U . Jurczyk b
a Conservative Dentistry and Periodontology Department ,
University of Medical Sciences , Bukowska 70 Street , 60-812 Poznan , Poland
b Division Mother's and Child's Health , University of Medical Sciences ,
Polna 33 Street , 60-535 Poznan , Poland
* karolajur@gmail.com
12.1 Introduction
The interactions between solid surfaces and cells are crucial to many
biological phenomena for all biomaterials. This chapter provides an
overview of metallic and ceramic biomaterials, along with a discussion
of microstructure and surface changes that promote biocompatibility.
For a material to be deemed biocompatible, any adverse reactions
which may ensue at the blood/material or tissue/material interface
must be minimal, while resistance to biodegeneration must be high.
Implantable materials should not [27]: cause thrombus-formations,
destroy, or sensitize the cellular elements of blood, alter plasma
proteins (including enzymes) so as to trigger undesirable reactions,
cause adverse immune responses, cause cancer and eratological
effects, produce toxic and allergic responses, deplete electrolytes,
 
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