Biomedical Engineering Reference
In-Depth Information
this study, small-angle neutron scattering (SANS) was employed to examine the mesh
size of the
fibre dimensions prior to freeze-drying. These
studies revealed that addition of Ca 2+ and chondroitin modi
fibrous networks and of the
ers increased
bre compact-
ness and thickness, respectively.
11.4
Conclusions
Future development of
physical gels will continue, although we anticipate that the
majority of novel applications will be in the biomedical area, not least because here the
'
'
smart
'
will no doubt
continue to be fashioned because of the potential of these gels in all aspects of nano-
technology. A considerable variety of physical and chemical cross-linking methods have
been evaluated for application in products employed in various environments, and in both
traditional and novel pharmaceutical areas. Innovative products have resulted from the
molecular and supramolecular properties of networks of associating biological and syn-
thetic polymers, and, in parallel with improvements in processing routes, exploit the
various cross-linking mechanisms. For example, scaffold applications have already made
quite dramatic progress, and a number of whole-body organs have been prepared using this
approach. Physical gels have already contributed to numerous applications in everyday life
so that, in our view, innovative products are already more advanced than aspects of
understanding. However, we believe that this will stimulate further debate and initiate
more thorough investigation of the underlying mechanisms of gelation. Finally, we expect
the interplay between the system creators (in most cases synthetic chemists or biochemists)
and concerned theorists to continue. We conclude with the hope that our topic will help to
stimulate further such cross-disciplinary interactions.
added value
'
is highest. Exciting new
'
architectures
'-
as described above
-
References
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