Biomimetic Preparation and Morphology Control of Mesoporous Silica - Biomimetics: Advancing Nanobiomaterials and Tissue Engineering - page 316

(278,200,2) (27,386,67)

Multi-lamellar fragments MCM-48 slices

MCM-41 particles
Single-phase region
Bi-phase region
Experimental point

Spherical morphology
Bi-continuous
Emulsion vesicles
Slices

Diethyl
ether, (y)

150 nm

( a )

50 nm

( b )

y = 456 ml

(14,432,34)

(80,200,200) (80,200,200)

(26,370,64)

250 nm

50 nm

( a ) (278,200,2) (180,200,100)

(70,240,170)
(80,200,200)

90 nm 40 nm

( c ) ( d )

II. y = 200 ml

(260,20,200)

Figure 12.5

(80,200,200) (35,360,85)

y = 33.6 ml (240,40,200)

(260,20,200)

Water (x)

Aqueous ammonia (z)

Water %

145 nm

125 nm

( a ) ( b )

Figure 12.1

(70,240,170) (80,200,200)

175 nm

( b )

930 nm

120 nm

( c )

100 nm

( d )

Figure 12.3 Figure 12.6

(278,200,2)

(278,200,2)

(240,40,200) (230,50,200)

(14,432,34) (14,432,34)

200 nm

60 nm

260 nm

860 nm

( a ) ( b )

125 nm

( a )

72 nm

( a ) ( b ) ( b )

(230,200,50) (230,200,50)

(230,200,50)

(23,400,57) (23,400,57)

(230,200,50)

280 nm

240 nm 60 nm

135 nm

45 nm

230 nm

( c ) ( c ) ( d )

( c ) ( d ) ( d )

(80,200,200) (80,200,200) (180,200,100) (180,200,100)

(240,40,200) (240,40,200)

50 nm

50 nm

250 nm

200 nm

( e )

120 nm 60 nm

( e ) ( f ) ( f ) ( e ) ( f )

Figure 12.2 Figure 12.4 Figure 12.7

Figure 13.12 (Figure 12.1) The phase diagram of reaction: products obtained
at varying reaction ratios of diethyl ether:water:aqueous ammonia. The points
marked in the diagram represent the volumes of H 2 O, C 2 H 5 OC 2 H 5 , NH 3 Æ H 2 O
(as x,y, z) of the initial experiments. Five typical structural features of multi-
lamellar silica fragments examined by HRTEM formed at the indicated reaction
ratios are shown between the brackets. (Figure 12.2) Highly ordered silica slices
(MCM-48); (Figure 12.3) Regular particle-like (MCM-41) silicas; (Figure 12.4)
multi-lamellar silica fragments; (Figure 12.5) spherical particles; (Figure 12.6)
vesicle-like silicas; (Figure 12.7) bi-continuously emulsified silicas. (Reprinted
with permission from [65])

MCM-48, or MCM-41), the radiolarian-like silica sphere as well as spheri-
cal mesoporous silica with hollow inner, slices, the fragments with lamel-
lar mesostructure, and bicontinuous mesostructure [60].

13.4.2.3 Alcohol-Water System

Monodispersed silica spheres with uniform size are widely applied to
fi elds including catalysts, bioseparation, and drug delivery, as well as
high-performance liquid chromatography (HPLC) [66-70]. In 1998 Grün
and Unger prepared mesoporous silica spheres based on Stöber's method