Biomedical Engineering Reference
In-Depth Information
100 nm
Figure 8.4 Transmission electron microscopy image of selenium nanoparticles
stabilized in bovine serum albumin and dispersed in water [66].
3 Hours
4 Hours
5 Hours
300,000
250,000
200,000
150,000
100,000
50,000
1
7.8 μ g/mL
15.5 μ g/mL
31 μ g/mL
Figure 8.5 Growth profi les of bacteria in the presence of selenium nanoparticles.
Data
3. * P < 0.05 compared with
3 hours (compared with the same selenium nanoparticle concentration group);
** P < 0.05 compared with 4 hours (compared with the same selenium
nanoparticle concentration group). There was no signifi cant difference in bacterial
densities between different selenium nanoparticle concentrations at each time
point tested. (Bacteria densities for control groups were 4,083,480, 11,662,534, and
15,315,887 cells/mL at 3, 4, and 5 hours, respectively). See [66] for more details.
=
Mean
±
standard deviation by mean, n
=
that the selenium nanoparticles synthesized by a simple colloidal method
strongly inhibited the growth of Staphylococcus aureus in solution com-
pared with no treatment. As mentioned before, bacterial biofi lms such as
those that form on implants, were considered even more diffi cult to be
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