Biomedical Engineering Reference
In-Depth Information
(
a
)
(
b
)
(
c
)
(
d
)
(
e
)
(
f
)
(
g
)
(
h
)
FC
B
HC
B
I
I
B
(
i
)
(
j
)
B
B
I
FC
I
(
k
)
(
l
)
Figure 5.3
Lateral radiographs of the distal femurs implanted with uncalcifi ed-
HAp/PLLA (u-HAp/PLLA) and calcifi ed HAp/PLLA (c-HAp/PLLA)
composites rods. (a) u-HA40/PLLA at 66 months after implantation,
(b) u-HA40/PLLA at 76 months after implantation, (c) u-HAp40/PLLA at
79 months after implantation, (d) u-HAp30/PLLA at 88 months after
implantation, (e) c-HAp40/PLLA at 66 months after implantation, (f) c-HAp40/
PLLA at 76 months after implantation, (g) c-HAp40/PLLA at 79 months after
implantation, (h) c-HAp30/PLLA at 88 months after implantation.
Histochemical analysis with Hematoxylin-eosin staining of decalcifi ed sections
of the distal femurs. (i, j) u-HAp30 at 88 months after implantation, (k) c-HAp40
at 79 months after implantation, (l) c-HAp40 at 76 months after implantation.
Although there were limited numbers of samples, histology of the u-HAp was
similar to c-HAp. Remodelled trabecular bone encircled the residual material. The
rod had been infi ltrated by a few histiocytes. The rods had been phagocytosed by
histiocytes transformed to foam cells. No infection or infl ammatory reaction were
seen in the follow-up period. B
=
bone; I
=
implant; HC
=
histiocyte; FC
=
foam
cell (original magnifi cation; (i, j)
×
20, bar
=
1000
m
m, high magnifi cation;
(k, l)
×
100, bar
=
100
m
m). Reprinted with permission from [75].
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