Biomedical Engineering Reference
In-Depth Information
Table 5.2
Typical examples of synthetic and natural biodegradable polymers used as matrices for nanocomposites
preparation and their applications in bone tissue engineering.
Polymer-
Nanocomposites
Polymers
Structure
Comments
Bone tissue engi-
neering (e.g.,
rods, miniscrews,
miniplates).
Poly((L)-lactic
acid) (PLLA)
PLLA/HAp
[74-77]
O
n
O
Polycaprolactone
(PCL)
PCL/HAp
[86-88]
In vitro
cellular growth
for bone repair.
O
n
O
Poly(lactide-
co-glycolide)
(PLGA)
in vivo
submaxilla
bone formation (rab-
bit model).
O
O
PLGA/HAp [95]
n
m
O
O
Poly(propylene
fumarate)
(PPF)
O
O
In vitro
osteoblast
differentiation.
HO
PPF/TCP [96].
O
O
OH
n
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