Biomedical Engineering Reference
In-Depth Information
Inverse analysis of the aspiration measurements enabled defining a representative
liver model including Glisson's capsule and parenchyma. The results of this work
can also be used as a relevant benchmark for simulation of the mechanical behavior
of human liver.
The cases in which aspiration data can provide diagnostic information were iden-
tified. The aspiration technique was shown to yield to a sensitivity similar to the one
of (un-blinded) digital palpation by an experienced surgeon.
As a note, by now the aspiration technique has been further developed for ap-
plication during laparoscopy. Technical details for this novel setup and first results
from corresponding
in vivo
measurements are found in Hollenstein et al. (
2011
).
Acknowledgements
We thank Dr. S. Breitenstein, University Hospital Zurich, for performing
the intraoperative measurements with the aspiration device. This work was partly supported by the
CO-ME/NCCR research network of the Swiss National Science Foundation.
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