Biomedical Engineering Reference
In-Depth Information
Fig. 13.5
Coupled excitation-induced contraction of generic heart model. Snapshots of the de-
formed model depict the action potential contours at different stages of repolarization. The
yellow
lines
denote the spatial orientation
f
of contractile myofibers. The two slices in the translucent
images in the
lower row
favorably depict the wall thickening and the twisting motion of the heart
has been demonstrated by the fully coupled finite element analysis of a generic heart
model.
Acknowledgements
The research by SG leading to these results has received funding from
the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement no:
PCIG09-GA-2011-294161. Work of EK has received financial support from the National Science
Foundation CAREER award CMMI-0952021 and from the National Institutes of Health Grant U54
GM072970.
References
Aliev RR, Panfilov AV (1996) A simple two-variable model of cardiac excitation. Chaos Solitons
Fractals 7:293-301
Ambrosi D, Arioli G, Nobile F, Quarteroni A (2011) Electromechanical coupling in cardiac dy-
namics: the active strain approach. SIAM J Appl Math 71:605-621
Ask A, Menzel A, Ristinmaa M (2012a) Electrostriction in electro-viscoelastic polymers. Mech
Mater 50:9-21
Ask A, Menzel A, Ristinmaa M (2012b) Phenomenological modeling of viscous electrostrictive
polymers. Int J Non-Linear Mech 47:156-165
Cherubini C, Filippi S, Nardinocchi P, Teresi L (2008) An electromechanical model of cardiac
tissue: constitutive issues and electrophysiological effects. Prog Biophys Mol Biol 97:562-573
