Biomedical Engineering Reference
In-Depth Information
11.5 Conclusion
Thoracic aneurysms with BAV and TAV both have significantly altered biomechan-
ical properties compared to normal ascending aorta, thus imparting their propen-
sity of AoD. Moreover, BAV ATAAs have lower delamination strength than TAV
ATAAs, rendering an apparently greater risk of AoD for BAV than TAV patients.
Acknowledgements The authors thank Mr. Jonathan Frank of the Center for Biologic Imaging
of the University of Pittsburgh for his technical assistance with SEM investigation and Mr. Michael
Eskay and Mr. Benjamin Green for assistance with aortic tissue acquisition and preparation. This
research was funded in part by a grant from Fondazione RiMED provided to Drs. Pasta and Vorp.
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