Biomedical Engineering Reference
In-Depth Information
2.1a.7 Problems
models of the circulatory, respiratory, and nervous sys-
tems are presented along withMATLAB implementations
of the computational models. Tools and techniques for
statistical and time series analysis are also presented with
applications of these methods.
As the physical scale of problems continues to de-
crease, the need for mathematical models of biomedical
systems continues to increase. The biomedical engineer
who masters the basic material such as presented here
will be well prepared to implement methods to solve
mathematical models of biomedical systems for the
steady-state, finite-time, or transient behavior of the
system. He or she will be able to combine his or her
analytical skills, computational skills, and mastery of the
link between the two, the numerical methods.
2.1a.1 List five applications of computers in BME and
briefly describe each application.
2.1a.2 You have been assigned the task of designing
a computerized patient-monitoring system for an in-
tensive-care unit in a medium-sized community hospital.
What parameters would you monitor? What role would
you have the computer play?
2.1a.3 Why is a computer-averaged, EEG-evoked
response signal easier to analyze than a raw signal?
2.1a.4 What advantage does a computer give in the
automated clinical laboratory?
2.1a.6 Lessons learned
in this chapter
2.1a.5 List the types of monitoring equipment normally
found in the ICU/CCU of a hospital.
2.1a.6 Are computer systems always applicable in bio-
medical equipment?
After studying this chapter, the BME student will have
learned the following:
Mathematical models are tools that biomedical
engineers use to predict the behavior of a system.
Biomedical engineers model systems in one or more
of three different states: steady-state behavior,
behavior over a finiteperiodof time, or transient behavior.
Derivation of mathematical models begins with a
conservation law.
Numerical methods are the bridge between analytical
formulation of the models (using algebra, calculus, or
differential equations) and computer implementation.
2.1a.7 Describe three computer applications in medical
research.
2.1a.8 On a BME examination, a student named George
computes in feet and inches the maximum distance that
a certain artificial heart design could pump blood
upward against gravity. Unfortunately, in recording this
distance on his examination paper, he reverses the
numbers for feet and inches. As a result, his recorded
answer is only 30% of the computed length, which was
less than 10 feet with no fractional feet or inches. What
length did George compute in feet and inches?
References
Enderle, J. D., Blanchard, S. M., and
Bronzino, J. D. 2000. Introduction to
Biomedical Engineering. San Diego, CA:
Academic Press.
Fournier, R. L. 1999. Basic Transport
Phenomena in Biomedical Engineering.
Philadelphia, PA: Taylor & Francis.
Gevertz, J. L., Dunn S. M., Roth, C. M.
2005. Mathematical model of real-time
PCR kinetics. Biotechnol. Bioeng .,
in press.
Hallett, M. (2000). Transcranial Magnetic
Stimulation and the Brain. Nature , 406:
147-150
Heldt, T., Shim, E. B., Kamm, R. D., Mark,
R. G. 2002. Computational modeling of
cardiovascular response to orthostatic
stress. J Appl Physiol ., Mar:92(3): 1239-
1254.
Melchior, F. M., Srinivasan, R. S., Charles,
J. B. 1992. Mathematical modeling of
human cardiovascular system for
simulation of orthostatic response. Am J
Physiol., 262(6 Pt 2):H1920-1933.
Norton, S. J. 2003. Can ultrasound be used
to stimulate nerve tissue? Biomed. Eng.
Online , 4:2(1):6.
Nebeker, F. (2002). Golden
accomplishments in biomedical
engineering. IEEE Engineering in
Medicine and Biology Magazine ,
21:17-47.
Pormann, J. B., Henriquez, C.S., Board,
J. A., Rose, D. J., Harrild, D.M.,
and Henriquez, A. P. 2000.
Computer Simulations of Cardiac
Electrophysiology. Article No. 24,
Proceedings of the 2000
ACM/IEEE Conference on
Supercomputing . Dallas, TX.
Thompson, W. J. 2000. Introduction to
Transport Phenomena . Upper Saddle
River, NJ: Prentice Hall PTR.
Vierstraete, A. 1999. http://users.
ugent.be/~avierstr/principles/
pcr.html . Last viewed August
24, 2005.
Search WWH ::




Custom Search