Biomedical Engineering Reference
In-Depth Information
TABLE 8.1 Antiretroviral Drugs Used in the Treatment of HIV Infection
Time to
Approval
(Months)
Manufacturer
Name
Approval
Date
Brand Name Generic Name
Multiclass combination products
Atripla
Efavirenz, emtricitabine
and tenofovir disoproxil
fumarate
Bristol-Myers
Squibb and
Gilead Sciences
12-July-06
2.5
Nucleoside reverse transcriptase inhibitors (NRTIs)
Combivir
Lamivudine and
zidovudine
GlaxoSmithKline
27-Sep-97
3.9
Emtriva
Emtricitabine, FTC
Gilead Sciences
02-Jul-03
10.0
Epivir
Lamivudine, 3TC
GlaxoSmithKline
17-Nov-95
4.4
Epzicom
Abacavir and lamivudine
GlaxoSmithKline
02-Aug-04
10.0
Hivid
Zalcitabine,
dideoxycytidine, ddC
Hoffmann-La
Roche
19-Jun-92
7.6
Retrovir
Zidovudine,
azidothymidine, AZT,
ZDV
GlaxoSmithKline
19-Mar-87
3.5
Trizivir
Abacavir, zidovudine, and
lamivudine
GlaxoSmithKline
14-Nov-00
10.9
Truvada
Tenofovir disoproxil
fumarate and
emtricitabine
Gilead Sciences,
Inc.
02-Aug-04
5.0
Videx EC
Enteric coated didanosine,
ddI EC
Bristol-Myers
Squibb
31-Oct-00
9.0
Videx
Didanosine,
dideoxyinosine, ddI
Bristol-Myers
Squibb
9-Oct-91
6.0
Viread
Tenofovir disoproxil
fumarate, TDF
Gilead
26-Oct-01
5.9
Zerit
Stavudine, d4T
Bristol-Myers
Squibb
24-Jun-94
5.9
Ziagen
Abacavir sulfate, ABC
GlaxoSmithKline
17-Dec-98
5.8
Nonnucleoside reverse transcriptase inhibitors (NNRTIs)
Intelence
Etravirine
Tibotec
Therapeutics
18-Jan-08
6.0
Rescriptor
Delavirdine, DLV
Pfizer
4-Apr-97
8.7
Sustiva
Efavirenz, EFV
Bristol-Myers
Squibb
17-Sep-98
3.2
Viramune
Nevirapine, NVP
Boehringer
Ingelheim
21-Jun-96
3.9
Protease inhibitors (PIs)
Agenerase
Amprenavir, APV
GlaxoSmithKline
15-Apr-99
6.0
Aptivus
Tipranavir, TPV
Boehringer
Ingelheim
22-Jun-05
6.0
(continued)
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