Biomedical Engineering Reference
In-Depth Information
46. Chigaev A, Waller A, Amit O, Halip L, Bologa CG, Sklar LA. Real-time analysis of
conformation-sensitive
antibody
binding
provides
new insights
into
integrin
conformational regulation. J. Biol. Chem. 2009;284(21):14337-14346.
47. Dennis MK, Bowles HJC, MacKenzie DA, Burchiel SW, Edwards BS, Sklar LA,
Prossnitz ER, Thompson TA. A multifunctional androgen receptor screening (MARS)
assay for the identification of compounds that modulate androgen receptor activity
using the high-throughput HyperCyt flow cytometry system. Cytometry 2008;73
(5):390-399.
48. HaynesMK, Strouse JJ,Waller A, LeitaoA, Curpan RF, Bologa C. Oprea TI, Prossnitz ER,
Edwards BS, Sklar LA, Thompson TA. Detection of intracellular granularity induction in
prostate cancer cell lines by small molecules using the HyperCyt high throughput flow
cytometry system. J. Biomol. Screen. 2009;14:596-609.
49. TessemaM, Simons PC, Cimino DF, Sanchez L, Waller A, Posner RG, Wandinger-Ness A,
Prossnitz ER, Sklar LA. Glutathione-S-transferase-green fluorescent protein fusion
protein reveals slow dissociation from high site density beads and measures free GSH.
Cytometry A 2006;69:326-334.
50. Schwartz SL, Tessema M, Pylypenko O, Rak A, Simons P, Surviladze Z, Sklar LA,
Wandinger-Ness A. Flow cytometry for real-time measurement of guanine nucleotide
binding and exchange by Ras-like GTPases. Anal. Biochem. 2008;381:258-266.
51. Surviladze Z, Waller A, Wu Y, Romero E, Edwards BS, Wandinger-Ness A, Sklar LA.
Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-
based multiplex assay. J. Biomol. Screen. 2010;15(1):10-20.
52. Roman DL, Ota S, Neubig RR. Polyplexed flow cytometry protein interaction assay: a
novel high-throughput screening paradigm for RGS protein inhibitors. J. Biomol. Screen.
2009;14(6):610-619.
53. Blazer LL, Roman DL, Muxlow MR, Neubig RR. Use of flow cytometric
methods
to
quantify
protein-protein
interactions. Curr.
Protoc. Cytom.
2010;51:13.11.1-13.11.15
54. Winter SS, Lovato DM, Khawaja HM, Edwards BS, Ivnitski-Steele ID, Young SM, Oprea
TI, Sklar LA, Larson RS. High throughput screening for daunorubicin-mediated drug
resistance identifies mometasone furoate as a novel ABCB1 reversal agent. J. Biomol.
Screen. 2008;13:185-193.
55. Ivnitski-Steele I, Larson RS, Lovato DM, Khawaja HM, Winter SS, Oprea TI, Sklar LA,
Edwards BS. High-throughput flow cytometry to detect selective inhibitors of ABCB1,
ABCC1, and ABCG2 transporters. Assay Drug Dev. Technol. 2008;6(2):263-276.
56. Nakamura K, Zawistowski JS, Hughes MA, Sexton JZ, Yeh LA, Johnson GL, Scott JE.
Homogeneous time-resolved fluorescence resonance energy transfer assay for
measurement of Phox/Bem1p (PB1) domain heterodimerization. J. Biomol. Screen.
2008;13(5):396-405.
57. KimK, Wang L, Hwang I. A novel flow cytometric high throughput assay for a systematic
study on molecular mechanisms underlying T cell receptor-mediated integrin activation.
PLoS One 2009;4(6):e6044.
58. Ivnitski-Steele I, Holmes AR, Lamping E, Monk BC, Cannon RD, Sklar LA. Identification
of Nile red as a fluorescent substrate of the Candida albicans ATP-binding cassette
transporters Cdr1p and Cdr2p and the major facilitator superfamily transporter Mdr1p.
Anal. Biochem. 2009;394(1):87-91.
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