Biomedical Engineering Reference
In-Depth Information
Each pixel in the main display (center, left) corresponds to a residue in the horizontal and vertical
sequences, with the darker pixels representing higher scores. The histogram window to the right of
the main display window supports the interactive adjustment of the display. The height of the
histogram peak indicates the quality of data, in that the higher the peak, the greater the signal-to-
noise ratio. The alignment panel along the bottom of the figure shows the actual sequence alignment
and supports interactive manipulation of the sequence positions.
Utilities
Most pattern-matching programs accept data in the FASTA format. Format conversion can be
performed manually with a text editor or a sequence editing utility such as READSEQ. A Web-based
version of READSEQ (see
Figure 8-19
) is available through the Bioinformatics & Molecular Analysis
Section (BIMAS) of the National Institutes of Health.
Figure 8-19. WWW READSEQ Format Conversion Utility (courtesy of
BIMAS).
