Biomedical Engineering Reference
In-Depth Information
BALSA determines the probability that a given pair of sequences should be aligned by sampling
alignments in proportion to their joint posterior probability. Probabilities are based on alignments
produced by specific combinations of substitution matrix, gap penalty, and gap extension. In
operation, the two sequences to be aligned are entered in FASTA format. BALSA supports copy-paste
as well as local file retrieval to populate the query and comparison sequences.
