Biomedical Engineering Reference
In-Depth Information
However, dot matrix methods are still studied because of the insight they provide into other
techniques, including dynamic programming.
Many of the other approaches to sequence alignment, such as the use of artificial neural networks,
genetic algorithms, Bayesian approaches, and Hidden Markov Models (HMMs), are either
experimental or combined with dynamic programming or word-based methods to provide users with
practical tools. Similarly, many adjunct technologies, such as scoring matrices, have become integral
to the operation of the major sequence alignment methods.
