Biomedical Engineering Reference
In-Depth Information
This chapter explores the application and methodology behind pattern matching, with a focus on
nucleotide and protein sequence alignment. The "
Fundamentals
" section explores the challenges of
sequence alignment, and the following five sections, from "
Dot Matrix Analysis
" to "
Bayesian
Methods
" review the key pairwise sequence alignment approaches. "
Multiple Sequence Alignment
"
extends the discussion to more challenging multiple sequence alignment tasks. The "
Tools
" section
examines the more popular of the Web-based tools available for sequence alignment. "
On the
Horizon
" explores the future of pattern matching, given the surge in proteomic research, and
"
Endnote
" considers the ultimate fate of user-directed pattern recognition, given the move to
intelligent agents and other technologies.
